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Etiological factor of vascular parkinsonism may be not only atherosclerosis or arteriosclerosis, but Eldepryl dosage (for example, 5mg), arteriovenous malformation, amyloid angiopathy, hereditary angiopathy and other vascular diseases. The cause of Parkinson's disease may be bilateral and multiple expansion perivascular spaces (etat crible) in the basal ganglia.
Vascular parkinsonism may develop after a stroke - acute or, more commonly, subacute - a few weeks or months (which indicates a role in the pathogenesis of generic Eldepryl syndrome), and further stabilize or regress. But in most cases, vascular parkinsonism develops gradually within distsirkulyatornoy encephalopathy, with periods of progression may alternate with periods of stabilization and improvement (step-over).
You can select multiple clinical variants of vascular parkinsonism.
The most common option - the so-called "lower body parkinsonism", appears only parkinsonopodobnym breach walk (Eldepryl side effects). It is characterized by difficulties in the beginning of the walk and when turning, hardening, small shuffling steps. In contrast to the classic parkinsonian gait, the patient walks, his legs wide apart, vigorously working on walking with his hands, not leaning forward, but rather leans back, visibly rocking in order Eldepryl. Such patients are not detected signs of akinesia and rigidity in the limbs, and walk in the genesis of disorders the dominant role, apparently, belongs to breach of postural mechanisms in connection with this syndrome than the right attitude to psevdoparkinsonizmu to mimic the diverse manifestations of akinetic-rigid syndrome.
